Background:

Duffy protein (CD234) is the receptor for the human malarial parasite Plasmodium vivax, simian malarial parasite Plasmodium knowlesi, and can bind chemokines. Duffy is an acidic glycoprotein that carries antigenic determinants of the Duffy blood group system, which consists of four alleles, five phenotypes and five antigens. Duffy protein is detectable in endothelial cells of postcapillary venules, epithelial cells of kidney collecting ducts, lung alveoli, thyroid, and Purkinje cells in the cerebellum.

Specificity:

DARC polyclonal antibody detects endogenous levels of DARC protein.

Alternative names:

Atypical chemokine receptor 1; Duffy antigen/chemokine receptor; Fy glycoprotein; GpFy; Glycoprotein D; Plasmodium vivax receptor; CD234; ACKR1; DARC; FY, GPD

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

A synthetic peptide corresponding to residues in Human DARC

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 36 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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