Background:

Olfactory receptors function by associating with odorant molecules to launch a neuronal response that elicits the perception of smell. Olfactory receptor genes are unevenly dispersed among 51 loci on 21 human chromosomes, and are composed of 172 subfamilies. OR6N1 (olfactory receptor, family 6, subfamily N, member 1), also known as olfactory receptor OR1-22, is a 312 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 1 family. As the largest family in the genome, the G-protein coupled receptor 1 family originated from single coding-exon genes. Encoded by a gene that maps to human chromosome 1q23.1, OR6N1 functions as an odorant receptor. Like many hormone and neurotransmitter receptors, OR6N1 shares a 7-transmembrane domain structure and recognizes G protein-mediated transduction of odorant signals.

Specificity:

OR6N1 polyclonal antibody detects endogenous levels of OR6N1 protein.

Alternative names:

Olfactory receptor 6N1; OR6N1

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

A synthetic peptide corresponding to residues in Human OR6N1

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 35 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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