Background:

MOBKL2A (Mps one binder kinase activator-like 2A), also known as MOB-LAK or MOB3A, is a 217 amino acid protein that regulates kinase activity. A member of the MOB1/phocein family, MOBKL2A is encoded by a gene that maps to human chromosome 19. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcå receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19.

Specificity:

MMOBKL2A/B polyclonal antibody detects endogenous levels of MMOBKL2A/B protein.

Alternative names:

MOB kinase activator 3A; MOB-LAK; Mob1 homolog 2A; Mps one binder kinase activator-like 2A; MOB3A; MOBKL2A; MOB kinase activator 3B; Mob1 homolog 2b; Mps one binder kinase activator-like 2B; MOB3B; MOBKL2B

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

A synthetic peptide corresponding to residues in Human MMOBKL2A/B

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 25 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

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