Background:

The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species. It also functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and control of gene expression. TGIF2LY (TGFB-induced factor homeobox 2-like, Y-linked), also known as TGIFLY, is a 185 amino acid testis-specific nuclear protein that functions as a transcriptional regulator during spermatid maturation. TGIF2LY belongs to the TALE/TGIF homeobox family and contains one homeobox DNA-binding domain. The gene encoding TGIF2LY maps within a male specific region of chromosome Y, in a region implied to form following a large X-to-Y transposition. The C-terminal region of TGIF2LY differs from the C-terminal region of its chromosome X homolog TGIF2LX, which suggests that TGIF2LY may act as a competitor or regulator of TGIF2LX.

Specificity:

TGIF2LY polyclonal antibody detects endogenous levels of TGIF2LY protein.

Alternative names:

Homeobox protein TGIF2LX; TGF-beta-induced transcription factor 2-like protein; TGFB-induced factor 2-like protein; X-linked; TGIF-like on the X; TGIF2LX; TGIFLX

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

A synthetic peptide corresponding to residues in Human TGIF2LY

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 21 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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