Background:

Complex 1 (also known as NADH dehydrogenase) of the electron transport chain (respiratory chain) is an enzymatic complex that catalyzes the transfer of electrons from NADH to ubiquinone. Free energy from the reaction is conserved in the transfer of protons into the intermembrane space to create an electrochemical proton gradient, a driving force for ATP synthesis. Complex 1 is a complicated, multi-protein, L-shaped complex composed of at least 45 different subunits and located in the mitochondrial inner membrane. NDUB7 (NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7), also known as NADH-ubiquinone oxioreductase B18 subunit, complex I-B18 (CI-B18) or cell adhesion protein SQM1, is a 137 amino acid accessory subunit of complex 1. Ubiquitously expressed, NDUFB7 localizes to the mitochondrial inner membrane on the matrix side. NDUFB7 contains a sevenfold repeat of positively-charged residues that may indicate a role in protein-protein interactions.

Specificity:

NDUFB7 polyclonal antibody detects endogenous levels of NDUFB7 protein.

Alternative names:

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7; Cell adhesion protein SQM1; Complex I-B18; CI-B18; NADH-ubiquinone oxidoreductase B18 subunit; NDUFB7

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

A synthetic peptide corresponding to residues in Human NDUFB7.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 16 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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