Background:

Ribosomal Protein L22 is also known as heparin-binding protein HBp15, because it binds heparin in the submandibular gland and brain. This small protein is also associated with two small nuclear RNAs called EBERs (Epstein- Barr encoded RNAs). These RNAs are synthesized in large amounts by human B lymphocytes infected with Epstein-Barr virus (EBV). Ribosomal protein L22, like L4, contains a globular domain that sits on the surface of the large ribosomal subunit and an extended loop that penetrates its core. These extensions contact multiple domains of 23S rRNA, indicating a potential, but not essential, role in rRNA folding during ribosomal assembly.

Specificity:

RPL22/RPL22L1 polyclonal antibody detects endogenous levels of RPL22/RPL22L1 protein.

Alternative names:

60S ribosomal protein L22-like 1; RPL22L1; 60S ribosomal protein L22; EBER-associated protein; EAP; Epstein-Barr virus small RNA-associated protein; Heparin-binding protein HBp15; RPL22

Species reactivity:

Human,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

A synthetic peptide corresponding to residues in Human RPL22.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 15 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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