Background:

TCEAL8 (transcription elongation factor A protein-like 8), also known as transcription elongation factor S-II protein-like 8, is a 117 amino acid nuclear protein that belongs to the TFS-II family and the TFA subfamily, and may be involved in transcriptional regulation. The gene that encodes TCEAL8 contains approximately 2,209 bases and maps to human chromosome Xq22.1. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of a X and Y chromosome leads to normal male development while two copies of X leads to normal female development. There are a number of conditions related to an unusual number and combination of sex chromosomes being inherited, including Turner’s syndrome, Klinefelter’s syndrome and Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.

Specificity:

TCEAL8 polyclonal antibody detects endogenous levels of TCEAL8 protein.

Alternative names:

Transcription elongation factor A protein-like 8; TCEA-like protein 8; Transcription elongation factor S-II protein-like 8; TCEAL8

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

A synthetic peptide corresponding to residues in Human TCEAL8.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 14 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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