Background:

LTA4H (Leukotriene A4-hydrolase) is a Zn2+-containing enzyme with both epoxide hydrolase and aminopeptidase activity (. As an epoxide hydrolase, LTA4H catalyzes the hydration of LTA4 to leukotriene B4 (LTB4, 5S,12R-dihydroxy-6,14-cis-8,10-trans-eicosatetraenoic acid), a potent lipid chemoattractant that influences inflammation, immune responses, and host defense against infection. As an aminopeptidase, LTA4H catalyzes the cleavage of amides of para-nitroaniline.

Specificity:

LTA4H polyclonal antibody detects endogenous levels of LTA4H protein.

Alternative names:

Leukotriene A(4) hydrolase; Leukotriene A-4 hydrolase; Leukotriene A4 hydrolaseprovided; LTA-4 hydrolase; LTA4; LTA4 hydrolase; LTA4H;

Species reactivity:

Human,Mouse

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human LTA4H.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 69 kDa

Applications:

WB IF

Usage:

WB: 1:500~1:2000 IF: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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