Background:

Nrg1 is a transcriptional repressor for glucose repression of STA1 gene expression in Saccharomyces cerevisiae. The NRG1 gene encodes a zinc finger protein which specifically binds to two regions in the upstream activation sequence of the STA1 gene. Nrg1 and its homolog Nrg2 function as negative regulators of invasive growth and as repressors of FLO11, which encodes a cell surface glycoprotein required for invasive growth.

Specificity:

NRG1 polyclonal antibody detects endogenous levels of NRG1 protein.

Alternative names:

Pro-neuregulin-1, membrane-bound isoform; Pro-NRG1; Neuregulin-1; Acetylcholine receptor-inducing activity; ARIA; Breast cancer cell differentiation factor p45; Glial growth factor; Heregulin; HRG; Neu differentiation factor; Sensory and motor neuron-derived factor; NRG1; GGF, HGL, HRGA, NDF, SMDF

Species reactivity:

Human,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

A synthetic peptide corresponding to residues in Human NRG1.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 100 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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