Background:

Fibrinogen silencer-binding protein, Function: Transcriptional repressor that down-regulates the expression of the fibrinogen gamma chain. Represses transcription of GSK3B gene promoter via its interaction with APBA1. Subunit structure: Interacts with APBA1 (via PDZ 1 and 2 domains). Subcellular location: Nucleus. Tissue specificity: Expressed in multiple tissues including brain. Miscellaneous: Intragenic, in the second intron of RAB54B gene.

Specificity:

FSBP polyclonal antibody detects endogenous levels of FSBP protein.

Alternative names:

Fibrinogen silencer-binding protein

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

A synthetic peptide corresponding to residues in Human BFSBP.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 34 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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