Bioworld Technology

Bioworld Technology is manufacturer of over 15,000 highly purified Monoclonal and Polyclonal Antibodies, Peptides, Proteins, and other related Research Products. Their products are used in all biological fields. An important focus in research taking place today is in work investigating Signal transduction pathways, Cardiac markers, Neuroscience as well as Stem cell research. Bioworld Technology is committed to providing customers with innovative research tools and to helping scientists determine the mechanisms of cell function and disease.
Bioworld Technology is one of the leading phospho-antibody manufacturers. They have produced over 500 phospho-antibodies for AKT, AMPK, GSK, STAT pathways. The peptides corresponding to each phospho-antibody have also been listed to help scientists.
All of their high quality antibodies, peptides and kits were tested in their own facility with original published pictures included. They have a commitment to customer service and offer 100% quality satisfaction. If our products do not match the results listed on the data sheet, we will help you to troubleshoot or refund for the full credit.
Bioworld Technology continues to manufacture product lines to the highest standards; and all of their scientists are dedicated to the mystery of the world of science.

FOXN1 polyclonal antibody BS60036

The add to cart button will appear once you select the values above

Specifications

size	50ul/100ul

Background:

The Fox family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. FOXN1, also designated Transcription factor winged-nude (WHN), is required for keratinocyte growth, as well as differentiation of epithelial progenitor cells in the thymic primordium into subcapsular, cortical, and medullary epithelial cells of the mature thymus. Mutations in the FOXN1 gene are responsible for nude, immune-deficient mice and rats. These nude mice are useful as hosts for xenografts in cancer research. The promoters for FOXN1 are active in the skin and thymus reflecting the critical role FOXN1 plays in the proper development of these tissues. Secreted Wnt glycoproteins appear to regulate FOXN1 transcription in the thymus. FOXN1 is expressed in the embryonic thymus after the common primordium is formed, beginning at E11.25. FOXN1 is also expressed at very low levels in normal human kidney and thyroid gland. In human, it is also expressed in the differentiating cells of the hair follicle precortex, the innermost layer of the outer root sheath, and the thymus.

Specificity:

FOXN1 polyclonal antibody detects endogenous levels of FOXN1 protein.

Alternative names:

Forkhead box protein N1; Winged-helix transcription factor nude; FOXN1; RONU; WHN

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

A synthetic peptide corresponding to residues in Human FOXN1.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 69 kDa

Applications:

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com