Background:

ZC3H11A (zinc finger CCCH domain-containing protein 11A), also known as KIAA0663 or ZC3HDC11A, is an 810 amino acid protein that contains 3 C3 H1-type zinc fingers. ZC3H11A is expressed in heart, brain, liver, skeletal muscle, kidney, pancreas, spleen, testis, ovary, fetal brain and fetal liver. The gene encoding ZC3H11A maps to human chromosome 1q32.1 and mouse chromosome 1 E4. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. The rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene on chromosome 1 which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

Specificity:

ZC3H11A polyclonal antibody detects endogenous levels of ZC3H11A protein.

Alternative names:

Zinc finger CCCH domain-containing protein 11A; KIAA0663; ZC3HDC11A

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 339-384 of Human ZC3H11A.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 89 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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