Background:

Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein L17, also known as RPL17, rpL23, PD-1 or 60S Ribosomal protein L17, is a 184 amino acid protein that is expressed in pancreas, lung, colon, cystic duct, gall bladder, kidney and liver and belongs to the ribosomal protein L22P family. Localized to the cytoplasm, it has been suggested that Ribosomal protein L17 may influence sexual differentiation of Area X and RA, potentially regulating the genesis and/or survival of neurons of juvenile zebra finches.

Specificity:

RPL17 polyclonal antibody detects endogenous levels of RPL17 protein.

Alternative names:

60S ribosomal protein L17; 60S ribosomal protein L23; PD-1

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 139-184 of Human RPL17.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 22 kDa

Applications:

WB IHC ICC

Usage:

WB: 1:500~1:1000 IHC: 1:50~1:200 ICC: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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