NOB1 monoclonal antibody MB64217
Specifications
| 50ul/100ul |
Background:
In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]). [supplied by OMIM, Nov 2010]. Transcript Variant: This variant (2) lacks an internal exon, compared to variant 1. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF; translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BG386829.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support ERS025081, ERS025082 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.
Specificity:
NIN1/PSMD8 binding protein 1 homolog
Alternative names:
ART-4; MST158; MSTP158; NOB1P; PSMD8BP1
Species reactivity:
Human, Mouse, Rat
Host:
Mouse
Ig type:
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Immunogen:
Human recombinant protein fragment corresponding to amino acids 2-234 of human NOB1(NP_054781) produced in E.coli.
Purification & Purity:
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Molecular weight:
46.5 kDa(Predicted)
Applications:
WB
Usage:
WB 1:2000
Storage:
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Precautions:
For research use only, not for use in diagnostic procedure.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
