Background:

NT3 is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. It is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NT3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse

Specificity:

neurotrophin 3

Alternative names:

HDNF; NGF-2; NGF2; NT-3; NT3

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Ig type:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Immunogen:

Recombinant protein expressed in E.coli corresponding to amino acids 139-257 of human NT3

Purification & Purity:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Molecular weight:

27.4 kDa(Predicted)

Applications:

IHC, WB

Usage:

WB: 1:5000, IHC 1:50, IF (1:100)

Storage:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Precautions:

For research use only, not for use in diagnostic procedure.

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