Background:

This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Specificity:

glial fibrillary acidic protein

Alternative names:

ALXDRD

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Ig type:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide

Immunogen:

Full-length protein expressed in 293T cell transfected with human GFAP expression vector

Purification & Purity:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Molecular weight:

49.88 kDa(Predicted)

Applications:

IF, IHC, WB

Usage:

WB 1:2000, IF 1:100

Storage:

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide

Precautions:

For research use only, not for use in diagnostic procedure.

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