Background:

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na(+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain.

Specificity:

NaV1.7 monoclonal antibody detects endogenous levels of NaV1.7 protein.

Alternative names:

hNE-Na, PN1, SCN9A, NENA, ETHA, GEFSP7, hNE Na, hNE-Na, hNENa, NE NA, NENA, Neuroendocrine sodium channel, Peripheral sodium channel 1, PN1, Scn9a, SCN9A, Sodium channel protein type 9 subunit alpha, Sodium channel protein type IX subunit alpha, Sodium channel voltage gated type IX alpha, Sodium channel voltage gated type IX alpha polypeptide, Sodium channel voltage gated type IX alpha subunit, Voltage gated sodium channel alpha subunit Nav1.7, Voltage gated sodium channel subunit alpha Nav1, Voltage-gated sodium channel subunit alpha Nav1.7,

Species reactivity:

Human

Host:

Mouse

Ig type:

Mouse Ig2b, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

226 kDa

Applications:

IHC ICC FC WB

Usage:

WB:1:500 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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