Background:

MTERFD1 belongs to the MTERF family which consists of four members including MTERF1, MTERF2, MTERF3 and MTERF4. Previous research showed that MTERFD1 is a mitochondrial protein that interacts with the mitochondrial DNA promoter region and decreases transcription initiation in mammalian mitochondria. This negative regulation is likely important for fine-tuning mitochondria transcription in response to physiological demands. Human mitochondrial transcription termination factor domain 1 (MTERFD1) was mutated in many types of cancer. In vivo and in vitro data indicated that MTERFD1 gene possesses oncogenic properties.

Specificity:

MTERFD1 monoclonal antibody detects endogenous levels of MTERFD1 protein.

Alternative names:

mTERF3, MTERF3, MTERFD1, CGI-12, CGI 12, mitochondrial, Mitochondrial transcription termination factor 3, MTER1, MTERF domain containing 1, mTERF domain containing protein 1 mitochondrial, mTERF domain-containing protein 1, mTERF3, Mterfd1, Transcription termination factor 3, mitochondrial,

Species reactivity:

Human, Mouse

Host:

Mouse

Ig type:

Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

48/38 kDa

Applications:

WB IHC ICC

Usage:

WB:1:1,000-1:2,000 IHC:1:50-1:200 ICC:1:50

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

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