Grp75 monoclonal antibody MB9255
Specifications
| 50ul/100ul |
Background:
The HSP 70 family comprises four highly conserved proteins, HSP 70, HSC 70, GRP 75 and GRP 78, which serve a variety of roles. HSC 70, GRP 75 and GRP 78 are constitutively expressed in primate cells. HSP 70 expression is strongly induced in response to heat stress. GRP 75 and GRP 78 are unresponsive to heat stress and are induced by glucose deprivation. GRP 75 expression is restricted to the mitochondrial matrix and aids in the translocation and folding of nascent polypeptide chains of both nuclear and mitochondrial origin. GRP 75 expression is restricted to the mitochondrial matrix and aids in the translocation and folding of nascent polypeptide chains of both nuclear and mitochondrial origin. GRP 75 and GRP 78 are unresponsive to heat stress and are induced by glucose deprivation.
Specificity:
Grp75 monoclonal antibody detects endogenous levels of Grp75 protein.
Alternative names:
GRP-75, MOT, PBP74, HSPA9, GRP75, HSPA9B, mt-HSP70, 75 kDa glucose regulated protein, 75 kDa glucose-regulated protein, CSA, Glucose Regulated Protein, Grp 75, GRP-75, GRP75, GRP75, Heat shock 70 kDa protein 9, Heat shock 70kD protein 9, heat shock 70kDa protein 9, Heat shock 70kDa protein 9B, Heat shock protein 74 kDa A, Heat shock protein A, Heat shock protein cognate 74, Hsc74, Hsp74, Hsp74a, HSPA9, Hspa9a, HSPA9B, MGC4500, mitochondrial, Mortalin 2, Mortalin, Mortalin perinuclear, Mortalin2, MOT 2, MOT, MOT2, Mthsp70, p66 mortalin, P66 MOT, PBP74, Peptide binding protein 74, Peptide-binding protein 74, Stress 70 protein mitochondrial, Stress 70 protein mitochondrial precursor, Stress-70 protein,
Species reactivity:
Human, Mouse, Rat
Host:
Mouse
Ig type:
Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Immunogen:
Peptide
Purification & Purity:
ProA affinity purified
Molecular weight:
74 kDa
Applications:
WB IHC ICC
Usage:
WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200
Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Precautions:
For research use only, not for use in diagnostic procedure.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com