Background:

CDCP1 (CUB-domain-containing protein 1) contains three extracellular CUB domains, a transmembrane domain, and two putative cytoplasmic tyrosine phosphorylation sites. Phosphorylation of the gp140 and p80 proteins is mediated by Src family kinases at various tyrosine residues, including Tyr 734. PTP family members mediate the desphosphorylation of CDCP1. The conversion of gp140 to p80 prolongs the phosphorylation state, which may affect signaling in epithelial wounds. CDCP1 acts as a marker for hematopoetic cells and also exhibits high expression in metastatic colon and breast tumors.

Specificity:

CDCP1 monoclonal antibody detects endogenous levels of CDCP1 protein.

Alternative names:

SIMA135, CD318, CDCP1, TRASK, 9030022E12Rik, AA409659, CD 318, CD_antigen=CD318, CD318, CD318 antigen, CDCP 1, Cdcp1, CDCP1, CUB domain containing protein 1, CUB domain-containing protein 1, E030027H19Rik, FLJ13772, FLJ22375, FLJ22969, Membrane glycoprotein gp140, MGC31813, OTTHUMP00000164120, OTTHUMP00000209568, RGD1305578, SIMA 135, SIMA135, Subtractive immunization M plus HEp3 associated 135 kDa protein, Subtractive immunization M plus HEp3-associated 135 kDa protein, Transmembrane and associated with src kinases, TRASK,

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Ig type:

Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein.

Purification & Purity:

Protein affinity purified.

Molecular weight:

92/72/37 kDa

Applications:

WB IHC ICC

Usage:

WB:1:500 ICC:1:50 IHC:1:50-1:100

Storage:

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com