Background:

The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet.

Specificity:

ALDH1A1 monoclonal antibody detects endogenous levels of ALDH1A1 protein.

Alternative names:

RALDH 1, RalDH1, ALDH1A1, ALDC, ALDH1, PUMB1, Acetaldehyde dehydrogenase 1, AHD2, AL1A1, ALDC, Aldehyde dehydrogenase 1 family member A1, Aldehyde dehydrogenase 1 soluble, Aldehyde dehydrogenase 1A1, Aldehyde dehydrogenase, Aldehyde dehydrogenase cytosolic, Aldehyde dehydrogenase family 1 member A1, Aldehyde dehydrogenase liver cytosolic, ALDH 1, ALDH 1A1, ALDH class 1, ALDH, liver cytosolic, ALDH-E1, ALDH1 A1, ALDH1, ALDH11, ALDH1A1, ALHDII, cytosolic, epididymis luminal protein 12, epididymis luminal protein 9, epididymis secretory sperm binding protein Li 53e, HEL-S-53e, MGC2318, PUMB1, RALDH 1, RalDH1, Retinal dehydrogenase 1,

Species reactivity:

Human, Rat

Host:

Mouse

Ig type:

Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein within human ALDH1A1 aa 5-200.

Purification & Purity:

ProG purified.

Molecular weight:

55 kDa

Applications:

WB IHC

Usage:

WB:1:2,000-1:10,000 IHC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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