Background:

GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. In particular, vimentin filaments are present at early developmental stages, while GFAP filaments are characteristic of differentiated and mature brain astrocytes. In addition, GFAP intermediate filaments are also present in nonmyelin-forming Schwann cells in the peripheral nervous system.

Specificity:

This antibody detects endogenous levels of GFAP and does not cross-react with related proteins.

Alternative names:

Glial fibrillary acidic protein

Species reactivity:

Human,Mouse,Rat

Host:

Mouse

Ig type:

Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

This antibody is produced by immunizing mice with a synthetic peptide (KLH-coupled) corresponding to a region of GFAP.

Purification & Purity:

Protein A affinity purified

Molecular weight:

~ 48 kDa

Applications:

WB IHCICCFC

Usage:

WB: 1:2000-1:5000 IHC/ICC:1:200 FC: 1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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