Background:

WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex,which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061).This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles

Specificity:

This antibody detects endogenous levels of MEP50 and does not cross-react with related proteins

Alternative names:

Methylosome protein 50; MEP-50; Androgen receptor cofactor p44; WD repeat-containing protein 77; p44/Mep50; WDR77; MEP50; WD45; HKMT1069; Nbla10071

Species reactivity:

Human,Mouse,Rat

Host:

Mouse

Ig type:

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human MEP50.

Purification & Purity:

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

Predicted band size:42KDa Observed band size:42KDa

Applications:

WB ICC

Usage:

WB: 1:1000 ICC: 1:50~200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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