Background:

Protein arginine N-methyltransferases,such as CARM1,catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine.Protein arginine methylation has been implicated in signal transduction,metabolism of nascent pre-RNA,and transcriptional activation.

Specificity:

This antibody detects endogenous levels of CARM1(C-terminus) and does not cross-react with related proteins

Alternative names:

PRMT4; CARM1; Coactivator associated arginine methyltransferase 1; Histone arginine methyltransferase; Histone-arginine methyltransferase CARM1; PRMT4; Protein arginine N methyltransferase 4.

Species reactivity:

Human,Mouse

Host:

Mouse

Ig type:

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to the C-terminus of Human CARM1.

Purification & Purity:

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

Predicted band size:63KDa Observed band size:63KDa

Applications:

WB IP

Usage:

WB: 1:200~500 IP: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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