LRRFIP1 monoclonal antibody MB0034
Specifications
| 50ul/100ul |
Background:
Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
Specificity:
This antibody detects endogenous levels of LRRFIP1 and does not cross-react with related proteins
Alternative names:
GC-binding factor 2; TAR RNA-interacting protein; GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1
Species reactivity:
Human,Mouse
Host:
Mouse IgG1
Ig type:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Immunogen:
Recombinant full length Human LRRFIP1.
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Molecular weight:
Predicted band size:89KDa Observed band size:160KDa
Applications:
WB
Usage:
WB: 1:1000
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Precautions:
For research use only, not for use in diagnostic procedure.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
