Background:

CKs provide the energy of phosphate hydrolysis necessary to drive the normal function of many cellular systems including muscle, electrocytes, retina photoreceptor cells, brain cells, kidney, salt glands, myometrium, placenta, pancreas, thymus, thyroid, intestinal epithelial cells, endothelial cells, cartilage and bone cells, macrophages, blood platelets, tumor and cancer cells. Human cytoplasmic CK-Brain (CK-B, BCK) is a 381 amino acid, brain tissue specific isoform of CK. Human cytoplasmic CK-Muscle (CK-M, MCK) is a muscle tissue specific isoform of CK. Human cytoplasmic CK-Mitochondrial (MtCK, Mi-CK) is a 416 amino acid mitochondrial specific isoform of CK. Cytosolic CKs are important in the energetic regulation of Ca2+-pumps and in the maintenance of Ca2+-homeostasis.

Specificity:

This antibody detects endogenous levels of CKMT1 and does not cross-react with related proteins

Alternative names:

Acidic-type mitochondrial creatine kinase; Mia-CK; Ubiquitous mitochondrial creatine kinase; U-MtCK; CKMT; CKMT1; UMTCK; CKMT1A

Species reactivity:

Human,Mouse

Host:

Mouse

Ig type:

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant full length Human CKMT1.

Purification & Purity:

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

Predicted band size:47KDa Observed band size:47KDa

Applications:

WB

Usage:

WB: 1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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