Background:

Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles.

Specificity:

This antibody detects endogenous levels of DCTN1 and does not cross-react with related proteins

Alternative names:

150 kDa dynein-associated polypeptide DAP-150; Dynactin 1; DCTN1; P135; DP-150; DAP-150; DCTN 1

Species reactivity:

Human

Host:

Mouse IgG2b

Ig type:

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to the N-terminal of Human Dynactin 1.

Purification & Purity:

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

Predicted band size:150KDa Observed band size:150KDa

Applications:

WB IP

Usage:

WB: 1:1000 IP: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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