Bioworld Technology

Bioworld Technology is manufacturer of over 15,000 highly purified Monoclonal and Polyclonal Antibodies, Peptides, Proteins, and other related Research Products. Their products are used in all biological fields. An important focus in research taking place today is in work investigating Signal transduction pathways, Cardiac markers, Neuroscience as well as Stem cell research. Bioworld Technology is committed to providing customers with innovative research tools and to helping scientists determine the mechanisms of cell function and disease.
Bioworld Technology is one of the leading phospho-antibody manufacturers. They have produced over 500 phospho-antibodies for AKT, AMPK, GSK, STAT pathways. The peptides corresponding to each phospho-antibody have also been listed to help scientists.
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SMC1 (Phospho-S957) polyclonal antibody BS94039

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Specifications

size	50ul/100ul

Background:

The SMC (structural maintenance of chromosomes) family of proteins form heterodimeric complexes that modulate sister chromatid cohesion and chromosome condensation for mitosis. The two distinct classes of SMC protein complexes are comprised of SMC1 (also designated SB1.8) with SMC3 (also designated HCAP for human chromosome-associated protein and Bamacan for the secreted proteoglycan), and SMC2 (also designated hCAP-E) with SMC4 (also designated hCAP-C). The SMC1/SMC3 complex is required for metaphase progression in mitotic cells and functions independently of the SMC2/SMC4 complex during the cell cycle. SMC1 is ubiqitiously expressed in various human tissues, including thymus, testis and colon. SMC3 is expressed as a nuclear protein in the colon, but can also occur as a secreted proteoglycan expressed in testis and brain. The secreted proteoglycan contains several glycosylation sites and is thought to play a role in basement membrane physiology.

Specificity:

SMC1 (Phospho-S957) polyclonal antibody detects endogenous levels of SMC1 protein only when phosphorylated at S957.

Alternative names:

SMC protein 1A, SMC-1-alpha, SMC-1A, SMC1A, SMC protein 1B, SMC-1-beta, SMC-1B, SMC1B, CDLS2, DKFZp686L19178, DXhXs423e, DXS423E, KIAA0178, MGC138332, OTTHUMP00000061876, RP6 29D12.1, SB1.8, Segregation of mitotic chromosomes 1, Segregation of mitotic chromosomes like 1, SMC 1, SMC protein 1B, SMC-1-beta, SMC-1B, SMC1, SMC1A, SMC1alpha, SMC1alpha protein, SMC1B, SMC1B, SMC1BETA, SMC1beta protein, SMC1L1, SMC1L2, SMCB, Structural maintenance of chromosome 1 like 1 protein, Structural maintenance of chromosome 1 like 2 protein, Structural maintenance of chromosomes 1A, Structural maintenance of chromosomes 1B, Structural maintenance of chromosomes protein 1B,

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic phospho-peptide corresponding to residues surrounding Ser957 of human SMC1.

Purification & Purity:

ProA affinity purified

Molecular weight:

160 kDa

Applications:

WB IHC ICC

Usage:

WB:1:1,000-1:5,000 IHC:1:50-1:200 ICC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com