Background:

Follistatin is a high affinity binding protein of Activin originally isolated for its role in regulating the release of follicle-stimulating hormone (FSH). Follistatin forms a group of interrelated factors with Activins and inhibins, members of the transforming growth factor β (TGFβ) superfamily. Activin, follistatin and Activin receptors are expressed in many tissues, where they function as autocrine/paracrine regulators of a variety of physiological processes including reproduction. Follistatin is an important regulator of pituitary FSH secretion.

Specificity:

Follistatin (R163) polyclonal antibody detects endogenous levels of Follistatin protein.

Alternative names:

Activin binding protein; Activin-binding protein; Follistatin; FS; fst; FST; Human follistatin gene

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 150-200 of Human Follistatin.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 70 kDa

Applications:

WB IHC

Usage:

WB: 1:500~1:1000 IHC: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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