Background:

Acts as a zinc-influx transporter (Potential). May be partly involved in the outbreak of schizophrenia. On the basis of sequence homology, the human SLC39A12 gene has been included as a member of a family of zinc (Zn) transporters designated as the ZRT-IRT-like proteins (current designation SLC39). ZRT-IRT-like proteins act in concert with another family of transporters, known in non-mammalian organisms as cation diffusion facilitators and in mammals as zinc transporters (ZnT), to regulate the distribution of Zn in the extra- versus intracellular milieu and within cellular compartments. Hence the ZnT maintain Zn homeostasis that is critical for the normal functioning of tissues including the CNS.

Specificity:

ZIP12 polyclonal antibody detects endogenous levels of ZIP12 protein.

Alternative names:

LZT-Hs8, ZIP-12, SLC39A12, ZIP12, bA570F3.1, FLJ30499, LIV 1 subfamily of ZIP zinc transporter 8, LIV-1 subfamily of ZIP zinc transporter 8, LZT Hs8, LZT-Hs8, LZTHs8, MGC43205, MGC51099, S39AC, SLC39A12, Solute carrier family 39 (metal ion transporter) member 12, Solute carrier family 39 (zinc transporter) member 12, Solute carrier family 39 member 12, Zinc transporter ZIP12, ZIP 12, ZIP-12, ZIP12, Zrt and Irt like protein 12, Zrt- and Irt-like protein 12,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Peptide

Purification & Purity:

Peptide affinity purified

Molecular weight:

70 kDa

Applications:

WB,IHC

Usage:

WB 1:2000 - 1:5000 IHC 1:50 - 1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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