WSTF polyclonal antibody BS91455
Specifications
| 50ul/100ul |
Background:
Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator. Involved in DNA damage response by phosphorylating 'Tyr-142' of histone H2AX (H2AXY142ph). H2AXY142ph plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes. In the complex, it mediates the recruitment of the WICH complex to replication foci during DNA replication.
Specificity:
WSTF polyclonal antibody detects endogenous levels of WSTF protein.
Alternative names:
BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF, baz1b, BAZ1B, Bromodomain adjacent to zinc finger domain protein 1B, hWALP 2, hWALP-2, hWALP2, transcription factor WSTF, Tyrosine-protein kinase BAZ1B, WALP-2, WALP2, WBRS 9, WBRS-9, WBRS9, WBSC 10, WBSC-10, WBSC10, WBSCR10, WBSCR9, Williams Beuren syndrome chromosome region 9 protein, Williams syndrome transcription factor, Williams-Beuren syndrome chromosomal region 10 protein, Williams-Beuren syndrome chromosomal region 9 protein, WSTF,
Species reactivity:
Human, Mouse, Rat
Host:
Rabbit
Ig type:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Immunogen:
Purification & Purity:
ProA affinity purified
Molecular weight:
171 kDa
Applications:
WB FC
Usage:
WB:1:500-1:1,000 FC:1:50-1:100
Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Precautions:
For research use only, not for use in diagnostic procedure.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
