Background:

Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.

Specificity:

WDR5 polyclonal antibody detects endogenous levels of WDR5 protein.

Alternative names:

WDR5, BIG3, 2410008O07Rik, AA408785, AA960360, BIG 3, Big, BIG3, BMP2 induced 3 kb gene protein, BMP2 induced gene, 3-KB, BMP2-induced 3-kb gene protein, MGC114572, OTTHUMP00000162494, SWD 3, SWD3, SWD3 Set1c WD40 repeat protein homolog, WD repeat containing protein 5, WD repeat domain 5, WD repeat protein 5, WD repeat-containing protein 5, WD repeat-containing protein BIG-3, WDR 5, Wdr5, WDR5,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

36 kDa

Applications:

WB IHC FC

Usage:

WB:1:500-1:1,000 IHC:1:50-1:200 FC:1:50-1:100

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com