Background:

Ubiquitin-specific protease 36 is an enzyme that in humans is encoded by the USP36 gene. This gene encodes a member of the ubiquitin-specific protease family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the nucleoli and deubuquitinate nucleophosmin and fibrillarin. May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4).

Specificity:

USP36 polyclonal antibody detects endogenous levels of USP36 protein.

Alternative names:

USP36, KIAA1453, Deubiquitinating enzyme 1, Deubiquitinating enzyme 36, DUB1, FLJ12851, KIAA1453, Ubiquitin carboxyl-terminal hydrolase 36, Ubiquitin specific peptidase 36, Ubiquitin specific processing protease 36, Ubiquitin thioesterase 36, Ubiquitin thiolesterase 36, Ubiquitin-specific-processing protease 36, UBP36, Usp36,

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Peptide

Purification & Purity:

Peptide affinity purified

Molecular weight:

123 kDa

Applications:

ICC IHC

Usage:

ICC:1:50-1:200 IHC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com