USP22 polyclonal antibody BS91415
Specifications
| 50ul/100ul |
Background:
The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP22 (ubiquitin specific peptidase 22), also known as USP3L, is a 525 amino acid protein that contains one UBP-type zinc finger and functions to catalyze the conversion of a ubiquitin C-terminal thioester to free ubiquitin and thiol, a reaction that may influence several cellular processes. Via its catalytic activity, USP22 is thought to play an important role in cell cycle progression and may also serve as a cancer stem cell marker. The gene encoding USP22 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.
Specificity:
USP22 polyclonal antibody detects endogenous levels of USP22 protein.
Alternative names:
USP22, KIAA1063, USP3L, Deubiquitinating enzyme 22, KIAA1063, Ubiquitin carboxyl terminal hydrolase 22, Ubiquitin carboxyl-terminal hydrolase 22, Ubiquitin specific peptidase 22, Ubiquitin specific peptidase 3 like, Ubiquitin specific processing protease 22, Ubiquitin specific protease 22, Ubiquitin thioesterase 22, Ubiquitin thiolesterase 22, Ubiquitin-specific-processing protease 22, UBP22, USP 22, Usp22, USP3L,
Species reactivity:
Human
Host:
Rabbit
Ig type:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Immunogen:
Recombinant protein
Purification & Purity:
ProA affinity purified
Molecular weight:
60 kDa
Applications:
WB ICC/IF FC IP
Usage:
WB:1:1,000-1:5,000 ICC:1:50-1:200 FC:1:50-1:100 IP:1:10-1:50
Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Precautions:
For research use only, not for use in diagnostic procedure.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com