Background:

The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP13 (ubiquitin specific peptidase 13), also known as ISOT3 (Isopeptidase T-3), is an 863 amino acid protein that belongs to the peptidase C19 family and contains one UBP-type zinc finger and two UBA domains. Highly expressed in testicular and ovarian tissue, USP13 functions to catalyze the water-dependent conversion of a ubiquitin C-terminal thioester to a thiol and a free ubiquitin.

Specificity:

USP13 polyclonal antibody detects endogenous levels of USP13 protein.

Alternative names:

ISOT-3, USP13, ISOT3, Deubiquitinating enzyme 13, Isopeptidase T 3, Isopeptidase T-3, Isopeptidase T3, ISOT 3, ISOT-3, ISOT3, Ubiquitin carboxyl terminal hydrolase 13, Ubiquitin carboxyl-terminal hydrolase 13, Ubiquitin specific peptidase 13 (isopeptidase T3), Ubiquitin specific peptidase 13, Ubiquitin specific processing protease 13, Ubiquitin specific protease 13, Ubiquitin thioesterase 13, Ubiquitin thiolesterase 13, Ubiquitin-specific-processing protease 13, UBP13, UBP13, USP 13, USP13,

Species reactivity:

Human, Mouse

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

97 kDa

Applications:

WB ICC/IF FC IP

Usage:

WB:1:500-1:2,000 ICC:1:50-1:200 FC:1:50-1:100 IP:1:10-1:50

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com