Background:

The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP10 (ubiquitin specific peptidase 10), also known as UBPO, is a 798 amino acid protein that belongs to the ubiquitin-specific protease family of cysteine proteases. Expressed in a variety of tissues, USP10 functions to catalyze the cleavage of ubiquitin from ubiquitin-conjugated protein substrates, possibly playing a role in the activity of the DNA-bound androgen receptor complex.

Specificity:

USP10 polyclonal antibody detects endogenous levels of USP10 protein.

Alternative names:

USP10, KIAA0190, Deubiquitinating enzyme 10, KIAA0190, MGC124997, MGC2621, Ubiquitin carboxyl terminal hydrolase 10, Ubiquitin carboxyl-terminal hydrolase 10, Ubiquitin specific peptidase 10, Ubiquitin specific processing protease 10, Ubiquitin specific protease 10, Ubiquitin thioesterase 10, Ubiquitin thiolesterase 10, Ubiquitin-specific-processing protease 10, UBP10, UBPO, USP 10, USP10,

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

110 kDa

Applications:

WB ICC/IF IHC IP

Usage:

WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com