TXNRD1 polyclonal antibody BS91390
Specifications
| 50ul/100ul |
Background:
Thioredoxin (Trx) is a redox protein that is found in several species, such as bacteria, plants and mammals, and contains a conserved active site, consisting of Trp-Cys-Gly-Pro-Cys. Trx reductases (TrxR1 and TrxR2) are ubiquitous Ly noble flavoproteins that catalyze the NADPH-dependent reduction of Trx as well as several other oxidized cellular components. Mammalian Trx reductases are a part of a selenium-containing pyridine nucleotide-disulphide oxidoreductase family, which has a conserved catalytic site of Cys-Val- Asn-Val-Gly-Cys. TrxR1 and TrxR2 are also involved in the prevention of oxidative stress. Inhibition of TrxR activity may provide for potential treatments of cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases.
Specificity:
TXNRD1 polyclonal antibody detects endogenous levels of TXNRD1 protein.
Alternative names:
TR, GRIM-12, TXNRD1, GRIM12, KDRF, cytoplasmic, Gene associated with retinoic and IFN-induced mortality 12 protein, Gene associated with retinoic and interferon-induced mortality 12 protein, Gene associated with retinoid IFN induced mortality 12 protein, GRIM 12, GRIM-12, GRIM12, KDRF, KM 102 derived reductase like factor, KM-102-derived reductase-like factor, MGC9145, Oxidoreductase, Thioredoxin reductase 1, Thioredoxin reductase 1 cytoplasmic, Thioredoxin reductase GRIM 12, Thioredoxin reductase TR1, TR 1, TR, TR1, TRXR 1, TRXR1, TRXR1, TXNR, TXNRD 1, Txnrd1,
Species reactivity:
Human, Mouse, Rat
Host:
Rabbit
Ig type:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Immunogen:
recombinant protein
Purification & Purity:
ProA affinity purified
Molecular weight:
55 kDa
Applications:
WB ICC IHC IP FC
Usage:
WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100
Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Precautions:
For research use only, not for use in diagnostic procedure.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
