Background:

Troponin T type 2 (cardiac), also known as TNNT2, is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations of this gene may be associated with mild or absent hypertrophy and predominant restrictive disease, with a high risk of sudden cardiac death.

Specificity:

TNNT2 polyclonal antibody detects endogenous levels of TNNT2 protein.

Alternative names:

TnTc, cTnT, Cardiac muscle troponin T, Cardiomyopathy dilated 1D (autosomal dominant), Cardiomyopathy hypertrophic 2, CMD1D, CMH2, CMPD2, cTnT, LVNC6, MGC3889, OTTHUMP00000033864, OTTHUMP00000033865, OTTHUMP00000033866, OTTHUMP00000033867, OTTHUMP00000033870, OTTHUMP00000218095, RCM3, TNNT 2, TNNT2, TNNT2, TnTc, Troponin T cardiac muscle, Troponin T type 2 (cardiac), Troponin T type 2 cardiac, Troponin T, cardiac muscle, Troponin T2 cardiac,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide (KLH-coupled) within human TNNT2 1-100 aa.

Purification & Purity:

Peptide affinity purified

Molecular weight:

36 kDa

Applications:

WB IHC

Usage:

WB:1:5000 IHC:1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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