Background:

The synucleins, including α-synuclein (also designated NACP for nonamyloid component precursor), β-synuclein (also designated PNP 14 for phospho-neuroprotein 14) and γ-synuclein (also designated persyn or BCSG1 for breast cancer-specific gene 1) are presynaptic proteins abundant in neurons. Synucleins are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. α-Synuclein, identified as a component of Alzheimer's disease amyloid plaques, is localized to neuronal cell bodies and synapses. Coordinate expression of α-synuclein and β-synuclein may be important during hematopoetic cell differentiation. A mutant form of α-synuclein is found in patients with early onset Parkinson's disease. γ-Synuclein is associated with axonal pathology in Parkinson's disease.

Specificity:

Synucleinγ polyclonal antibody detects endogenous levels of Synucleinγ protein.

Alternative names:

SR, SNCG, BCSG1, PERSYN, PRSN, BCSG1, Breast cancer specific gene 1 protein, Breast cancer specific protein 1, Breast cancer-specific gene 1 protein, Gamma synuclein, Gamma-synuclein, Persyn, PRSN, SNCG, SR, Synoretin, Synuclein gamma, synuclein, gamma (breast cancer-specific protein 1), SYUG,

Species reactivity:

Human, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

16 kDa

Applications:

WB ICC IHC IP FC

Usage:

WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100 IHC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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