Background:

STAU1 (staufen, RNA binding protein, homolog 1) is a 577 amino acid protein that contains three double-stranded RNA-binding domains and is a mammalian homolog of Staufen, a Drosophila protein that is involved in mRNA transport during oogenesis and zygotic development. Localized to the rough endoplasmic reticulum (RER) and expressed in a variety of tissues, including heart, brain, liver, lung, pancreas, kidney and placenta, STAU1 binds to both Tubulin and double-stranded RNA and is thought to play an important role in mRNA transport from the microtubule network to the RER. Additionally, STAU1 may be involved in cross-linking cytoskeletal components with RNA, an event that is important for proper mRNA positioning during translation. Alternative splicing of the STAU1 gene yields two STAU1 isoforms, designated short and long.

Specificity:

Staufen polyclonal antibody detects endogenous levels of Staufen protein.

Alternative names:

STAU1, STAU, Double stranded RNA binding protein Staufen homolog 1, Double stranded RNA binding protein Staufen homolog, Double-stranded RNA-binding protein Staufen homolog 1, FLJ25010, MGC124588, PPP1R150, STAU, STAU1, STAU1, staufen, Staufen RNA binding protein (Drosophila), Staufen RNA binding protein homolog 1, Staufen, Drosophila, homolog of, 1, Staufen, RNA binding protein, homolog 1 (Drosophila), staufen-like,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

63 kDa

Applications:

WB ICC/IF FC

Usage:

WB:1:500-1:2,000 ICC/IF:1:50-1:200 FC:1:50-1:100

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com