SMC3 polyclonal antibody BS91259
Specifications
| 50ul/100ul |
Background:
The SMC (structural maintenance of chromosomes) family of proteins form heterodimeric complexes that modulate sister chromatid cohesion and chromosome condensation for mitosis. The two distinct classes of SMC protein complexes are comprised of SMC1 (also designated SB1.8) with SMC3 (also designated HCAP for human chromosome-associated protein and Bamacan for the secreted proteoglycan), and SMC2 (also designated hCAP-E) with SMC4 (also designated hCAP-C). The SMC1/SMC3 complex is required for metaphase progression in mitotic cells and functions independently of the SMC2/SMC4 complex during the cell cycle. SMC1 is ubiqitiously expressed in various human tissues, including thymus, testis, and colon. SMC3 is expressed as a nuclear protein in the colon, but can also occur as a secreted proteoglycan expressed in testis and brain. The secreted proteoglycan contains several glycosylation sites and is thought to play a role in basement membrane physiology.
Specificity:
SMC3 polyclonal antibody detects endogenous levels of SMC3 protein.
Alternative names:
SMC protein 3, SMC-3, Bamacan, hCAP, BAM, Bamacan, Basement membrane associated chondroitin proteoglycan, Basement membrane-associated chondroitin proteoglycan, BMH, CDLS3, chondroitin sulfate proteoglycan 6 (bamacan), Chondroitin sulfate proteoglycan 6, Chromosome associated polypeptide, Chromosome-associated polypeptide, CSPG 6, CSPG6, hCAP, Human chromosome associated polypeptide, im:7142991, SMC 3, SMC protein 3, SMC-3, smc3, SMC3, SMC3L1, Structural maintenance of chromosome 3, Structural maintenance of chromosomes 3, Structural maintenance of chromosomes protein 3, u:fb22e01, wu:fc30d07,
Species reactivity:
Human, Mouse, Rat
Host:
Rabbit
Ig type:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Immunogen:
recombinant protein
Purification & Purity:
ProA affinity purified
Molecular weight:
141 kDa
Applications:
WB ICC/IF IHC FC
Usage:
WB:1:1,000-1:5,000 ICC:1:100-1:500 IHC:1:50-1:200 FC:1:50-1:100
Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Precautions:
For research use only, not for use in diagnostic procedure.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
