Background:

Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. Defects in SGCD are the cause of limb-girdle muscular dystrophy type 2F (LGMD2F) [MIM:601287]. LGMD2F is an autosomal recessive disorder. Defects in SGCD are the cause of cardiomyopathy dilated type 1L (CMD1L) [MIM:606685]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.

Specificity:

Sarcoglycan delta polyclonal antibody detects endogenous levels of Sarcoglycan delta protein.

Alternative names:

Delta-SG, 35DAG, SGCD, 35 kDa dystrophin associated glycoprotein, 35 kDa dystrophin-associated glycoprotein, 35DAG, CMD1L, DAGD, Delta-sarcoglycan, Delta-SG, Dystrophin associated glycoprotein delta sarcoglycan, LGMD2F, MGC22567, Placental delta sarcoglycan, Sarcoglycan delta (35 kDa dystrophin associated glycoprotein), SG delta, SGCD, SGCD, SGCDP, SGD,

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

35 kDa

Applications:

WB IP IHC

Usage:

WB:1:500-1:2,000 IHC:1:50-1:200 IP:1:10-1:50

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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