Background:

Belongs to the ribonucleoside diphosphate reductase small chain family. Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.it have two regulatory sites: the specificity site, which controls substrate specificity, and the activity site which regulates overall catalytic activity. A substrate-binding catalytic site, located on M1, is formed only in the presence of the second subunit M2.

Specificity:

RRM2 polyclonal antibody detects endogenous levels of RRM2 protein.

Alternative names:

RRM2, RR2, cb111, chunp6884, etID309896.20, R2, reductase M2 polypeptide variant 1, reductase M2 polypeptide variant 2, reductase M2 polypeptide variant 3a, reductase M2 polypeptide variant 3b, reductase M2 polypeptide variant 3c, reductase M2 polypeptide variant 3d, Ribonucleoside-diphosphate reductase subunit M2, Ribonucleotide reductase M2, Ribonucleotide reductase M2 polypeptide, Ribonucleotide reductase M2 subunit, ribonucleotide reductase protein r2 class I, Ribonucleotide reductase regulatory subunit M2, Ribonucleotide reductase small chain, Ribonucleotide reductase small subunit, Ribonucleotide reductase, R2 subunit, RIR2, RR2, RR2M, RRM2,

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

45 kDa

Applications:

WB IP ICC/IF

Usage:

WB:1:500-1:2,000 ICC:1:20-1:50 IP:1:10-1:50

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

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