Background:

Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses.

Specificity:

PSD93 polyclonal antibody detects endogenous levels of PSD93 protein.

Alternative names:

Chapsyn-110, DLG2, Channel associated protein of synapse 110, Channel associated protein of synapses 110kD, Channel-associated protein of synapse-110, Chapsyn 110, Chapsyn-110, Chapsyn110, Discs, large homolog 2 (Drosophila), Disks large homolog 2, DKFZp781D1854, DKFZp781E0954, Dlg 2, dlg2, DLG2, Dlgh 2, Dlgh2, FLJ37266, Gm1197, MGC131811, Postsynaptic density protein PSD 93, Postsynaptic density protein PSD-93, Postsynaptic density protein PSD93, PSD 93, PSD93,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

Applications:

WB FC IP

Usage:

WB:1:500-1:2,000 FC:1:50-1:100 IP:1:10-1:50

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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