Background:

Puromycin aminonucleoside nephrosis (PAN) is a rat model for human minimal change nephropathy. During PAN, severe proteinuria is induced that is paralleled by a reduced expression of a rat podocyte protein, named podoplanin. Podoplanin, also known as glycoprotein 38 (gp38) is a type I membrane protein. Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes.

Specificity:

Podoplanin polyclonal antibody detects endogenous levels of Podoplanin protein.

Alternative names:

Gp36, T1A, Aggrus, Glycoprotein 36 KD, Glycoprotein 36, gp 36, GP 38, GP 40, gp36, GP38, GP40, HT1A 1, HT1A1, hT1alpha 1, hT1alpha 2, hT1alpha1, hT1alpha2, Lung type I cell membrane associated glycoprotein, Lung type I cell membrane associated glycoprotein isoform a, Lung type I cell membrane associated glycoprotein T1A 2, OTS 8, OTS8, OTTHUMP00000009640, OTTHUMP00000044504, PA2.26, PA2.26 antigen, Pdpn, PDPN, Podoplanin, PSEC0003, PSEC0025, T1 alpha, T1 ALPHA GENE, T1-alpha, T1A 2, T1A, TI1A, TIA 2, TIA2,

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

36 kDa

Applications:

WB IHC

Usage:

WB:1:2,000-1:5,000 IHC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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Email: info@sobekbio.com

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