PGAM1 polyclonal antibody BS91061
Specifications
| 50ul/100ul |
Background:
Members of the PGAM (phosphoglycerate mutase) family of proteins are important components of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism. They are responsible for catalyzing the transfer of phospho groups between the carbon atoms of phosphoglycerates. In mammals there are two types of PGAM isozymes: PGAM1 (also known as PGAMB) and PGAM2 (also known as PGAMA). In the cell, PGAM1 and PGAM2 exist as either homodimers or heterodimers and are responsible for the interconversion of 3-phosphoglycerate and 2-phosphoglycerate. PGAM2 homodimers are expressed in skeletal muscle, mature sperm cells and heart; PGAM1 homodimers are found in most other tissues; and PGAM1/PGAM2 heterodimers are found exclusively in the heart. PGAM4, also known as PGAM3, is a protein formerly considered to be specific to humans. Initially the PGAM4 gene was described as a pseudogene but it is now known to encode a functional protein at least 25 million years old. The gene encoding PGAM4 is believed to have originated by retrotransposition, with the original copy being the PGAM1 gene.
Specificity:
PGAM1 polyclonal antibody detects endogenous levels of PGAM1 protein.
Alternative names:
PGAM-B, PGAM1, PGAMA, BPG dependent PGAM 1, BPG dependent PGAM1, BPG-dependent PGAM 1, OTTHUMP00000059414, PGAM 1, PGAM A, PGAM B, PGAM-B, PGAM1, PGAM1, PGAMA, PGAMB, Phosphoglycerate mutase 1, Phosphoglycerate mutase 1 brain, Phosphoglycerate mutase A, Phosphoglycerate mutase A nonmuscle form, Phosphoglycerate mutase isozyme B,
Species reactivity:
Human, Mouse, Rat
Host:
Rabbit
Ig type:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Immunogen:
Purification & Purity:
ProA affinity purified
Molecular weight:
29 kDa
Applications:
WB IHC FC
Usage:
WB:1:500-1:2,000 IHC:1:50-1:100 FC:1:50-1:100
Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Precautions:
For research use only, not for use in diagnostic procedure.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com