Background:

The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

Specificity:

PAX7 polyclonal antibody detects endogenous levels of PAX7 protein.

Alternative names:

PAX7, FLJ37460, HUP1, OTTHUMP00000002534, Paired box 7, Paired box gene 7, Paired box homeotic gene 7, Paired box protein Pax-7, Paired domain gene 7, Paired domain gene HuP1, Pax7, PAX7 transcriptional factor, PAX7/FKHR fusion gene, included, PAX7, PAX7B, RGD1564360, RMS2,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

57 kDa

Applications:

WB FC

Usage:

WB:1:1,000 FC:1:50-1:100

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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