Background:

Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH₂ terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxy terminal intracellular domains. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as -catenin, to regulate cadherin function. Members of this family of adhesion proteins include rat cadherin K (and its human homolog, cadherin, R-cadherin, B-cadherin, E/P cadherin and cadherin-5.

Specificity:

Pan-Cadherin polyclonal antibody detects endogenous levels of Pan-Cadherin protein.

Alternative names:

E-cadherin, CDH1, CDHE, UVO, CDH2, CDHN, NCAD, P-cadherin, CDH3, CDHP, VE-cadherin, CDH5, R-CAD, R-cadherin, Cadherin, CDH3, CDHP, 7B4 antigen, Cadherin-1, Cadherin-2, Cadherin-3, Cadherin-4, Cadherin-5, CAM 120/80, CD144, CD324, CD325, Cdh4, CDH5, CDHE, CDHN, E-cadherin, Epithelial cadherin, N-cadherin, NCAD, Neural cadherin, P-cadherin, Placental cadherin, UVO, Uvomorulin, Vascular endothelial cadherin,

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

140 kDa

Applications:

WB ICC/IF IHC IP FC

Usage:

WB:1:1,000-1:5,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

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