Background:

The constitutive transport element (CTE) of type D retroviruses serves as a signal of nuclear export for unspliced viral RNAs. TAP (tip-associating protein, also known as NXF1) mediates the export of CTE-containing simian type D retroviral RNAs through binding directly to the CTE. TAP is associated with a recognized mRNA export pathway and is a member of the multigene family of NXF proteins. NXF proteins belong to an evolutionarily conserved family of proteins, which are characterized by a leucine-rich-repeat domain (LRR) followed by a region known as the nuclear transport factor 2 (NTF2)-like domain.

Specificity:

NXF1 polyclonal antibody detects endogenous levels of NXF1 protein.

Alternative names:

NXF1, TAP, DKFZp667O0311, DmNXF1, MEX67, MEX67, yeast, homolog of, Mex67p, mRNA export factor TAP, Mvb1, Nuclear RNA export factor 1, Nuclear RNA export factor 1 homolog (S. cerevisiae), nxf 1, NXF1, NXF1, Protein small bristles, Sbr, TAP, Tip associating protein, Tip-associated protein, Tip-associating protein,

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein within c-terminal human NXF1.

Purification & Purity:

ProA affinity purified

Molecular weight:

70 kDa

Applications:

WB ICC IP

Usage:

WB:1:500-1:2,000 ICC:1:50-1:100 IP:1:10-1:50

Storage:

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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