Background:

Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells. Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function.

Specificity:

NFAT2 polyclonal antibody detects endogenous levels of NFAT2 protein.

Alternative names:

NF-ATc1, NFATc1, NF-ATc, NFATc, NFATC1, NFAT2, NFATC, cytoplasmic 1, MGC138448, NF ATc, NF ATc1, NF-ATc, NF-ATc1, NF-ATc1.2, NFAC1, NFAT 2, NFAT transcription complex cytosolic component, NFATC 1, NFATc, NFATc1, Nuclear factor of activated T cells cytoplasmic 1, Nuclear factor of activated T cells cytoplasmic calcineurin dependent 1, Nuclear factor of activated T cells cytosolic component 1, nuclear factor of activated T-cells 'c', Nuclear factor of activated T-cells,

Species reactivity:

Human

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

recombinant protein

Purification & Purity:

ProA affinity purified

Molecular weight:

101 kDa

Applications:

WB ICC IHC FC

Usage:

FC:1:50-1:100 WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:200

Storage:

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

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